How to access Leqvio from the UAE — the named-patient import pathway, 2026
By Reserve Meds · Clinical & regulatory team · Last reviewed 2026-04-23
A UAE patient with established atherosclerotic cardiovascular disease (ASCVD), heterozygous familial hypercholesterolaemia, or statin-intolerance who is not at LDL-C goal on maximally tolerated statin (with or without ezetimibe) may receive a prescription for Leqvio (inclisiran) from their treating cardiologist or lipidologist. Leqvio is FDA-approved for LDL-C lowering in these populations and is developed by Novartis. Leqvio is available in some UAE tertiary facilities, but formulary coverage is uneven; where your specific hospital formulary does not stock Leqvio or where the required dosing schedule is not coordinated in-house, the named-patient pathway is a legitimate bridge.
This guide explains how Reserve Meds supports access in that formulary-gap scenario and where we fit in.
The clinical situation
Leqvio is a small interfering RNA (siRNA) therapy targeting PCSK9 messenger RNA in hepatocytes, administered subcutaneously on a loading schedule (Day 0, Day 90) then every six months. Twice-yearly dosing is a meaningful adherence advantage versus weekly/biweekly PCSK9 monoclonal antibodies. Eligibility anchors to lipid panel history, ASCVD or HeFH documentation, and evidence of maximally tolerated statin therapy. Your cardiologist will confirm baseline LDL-C, set a follow-up lipid cadence, and document the clinical rationale.
Is Leqvio legally importable into the UAE?
Yes — via the UAE Ministry of Health and Prevention (MoHAP) named-patient import framework (with DoH Abu Dhabi / DHA Dubai parallel authority) when Leqvio is not on your specific hospital formulary or when the specific dosing coordination is not locally available.
The named-patient mechanism permits a UAE-licensed physician to import a medicine not routinely stocked at a given institution when (a) the medicine is approved by a recognised reference authority such as the US FDA, (b) no clinically equivalent alternative is available at that institution for the patient, (c) the physician accepts clinical responsibility, and (d) chain of custody is documented. For a formulary-gap case, the rationale emphasises the specific institution's unavailability and the patient's clinical need.
How the pathway works, step by step
- Consultation with your treating cardiologist or lipidologist. ASCVD / HeFH documentation, statin history, LDL-C trajectory, and clinical rationale.
- Baseline assessment. Full lipid panel, hepatic and renal function, and monitoring-cadence plan.
- MoHAP named-patient application. The physician or hospital pharmacy files clinical rationale (including the formulary-gap note), patient reference, and dosing schedule.
- US-side sourcing. Reserve Meds coordinates with our US-licensed specialty wholesale partner to secure Leqvio from authorised distribution under DSCSA.
- Cold-chain shipment. Leqvio ships with temperature control to the prescribing hospital pharmacy.
- Arrival and administration. The clinic administers the subcutaneous dose on the Day 0 / Day 90 / every-6-month cadence.
What documentation your physician needs
- Clinical rationale letter confirming indication (ASCVD / HeFH / statin-intolerance), maximally tolerated therapy history, and Leqvio as indicated therapy
- Verification of UAE medical license
- Lipid-panel history documenting LDL-C above goal
- Institutional note confirming formulary gap (if applicable)
- Planned dosing schedule (Day 0, Day 90, then every 6 months) and follow-up LDL-C cadence
Reserve Meds provides a physician documentation kit bundling MoHAP templates and the formulary-gap clinical-rationale language.
Costs and timing
Leqvio's US cash-pay reference cost sits in an indicative 2026 annual range of roughly USD 6,500–7,500 (two doses per year). International logistics, MoHAP documentation handling, cold-chain shipment, and concierge coordination add incremental cost. Reserve Meds issues a transparent quote at the start of intake. These figures are indicative, not guaranteed.
Indicative timing — not guaranteed — for first dose after cohort intake opens is approximately 14–28 days from the moment a complete MoHAP application is submitted.
Reserve Meds is in pre-launch. Fulfillment availability is limited to our first cohort, and all timelines published on this site are indicative. If your clinical situation is time-sensitive, flag that when you join the waitlist — we triage accordingly.
Reserve Meds's role
- Sourcing. Through our US-licensed specialty wholesale partner under DSCSA chain-of-custody.
- Documentation. Regulatory package for your physician and MoHAP review, including the formulary-gap rationale.
- Logistics. Validated cold-chain shipment to your prescribing hospital.
- Concierge case lead. A named point of contact coordinating the semi-annual dosing cadence.
What we do not do: We are not the prescriber, do not practise medicine, and are not the dispensing pharmacy. All clinical decisions remain with your treating cardiologist. We operate on a waitlist basis during pre-launch.
Frequently asked
My hospital already stocks Leqvio — do I need this pathway? No, if your hospital routinely stocks and dispenses Leqvio for your indication, use the local pathway. Reserve Meds steps in only where there is a formulary or supply gap.
How often do I dose after the loading phase? Day 0, Day 90, then every six months — a total of two maintenance doses per year.
How does Leqvio compare with Praluent or Repatha? All three are PCSK9-pathway therapies. Leqvio (siRNA) is dosed twice yearly; Praluent and Repatha (monoclonal antibodies) are dosed every 2–4 weeks. Your cardiologist selects based on adherence profile and clinical picture.
Will insurance cover this? Cash-pay is the default for named-patient imports. Some UAE private insurers consider case-by-case reimbursement; we supply documentation but do not process claims directly.
Next step — join the first-cohort waitlist
Reserve Meds is opening to a limited first cohort in 2026. Add your case to the waitlist and our concierge case lead will reach out when we enter intake for Leqvio coordination.
Add me to the Leqvio waitlist> Examples and timings above are composite illustrations drawn from published sources and typical named-patient patterns. Your individual case is assessed by your physician and our clinical-regulatory team; Reserve Meds does not guarantee outcomes or timelines.
Reserve Meds is a US-based concierge coordinator for cross-border specialty medicine. We are in pre-launch; service availability is limited to our first cohort and published timelines are indicative, not guarantees. Cash-pay. Export-only (US → overseas). Composite case examples. Not medical advice.
Clinical & regulatory review: Reserve Meds clinical team and AI regulatory-counsel review pipeline. Last medically reviewed: 2026-04-23.