Wayrilz (rilzabrutinib), immune thrombocytopenia access
Persistent or chronic immune thrombocytopenia (ITP) in adults with insufficient response to a previous treatment ยท Hematology (immune thrombocytopenia)
About Wayrilz
Wayrilz (rilzabrutinib) is an oral reversible covalent Bruton's tyrosine kinase (BTK) inhibitor from Sanofi, originally developed by Principia Biopharma. It is indicated for adults with persistent or chronic immune thrombocytopenia (ITP) who have had an insufficient response to a previous treatment. It earned US FDA approval in 2025.
Rilzabrutinib's reversible binding profile distinguishes it from earlier irreversible BTK inhibitors and supports a dual mechanism in ITP, modulating both autoantibody-driven platelet destruction (via B-cell and Fc-receptor signalling) and inflammatory macrophage activity, without targeting platelets directly.
Where Wayrilz is not yet registered in a patient's home country, Reserve Meds coordinates supply from US specialty wholesalers via Named Patient Program (NPP) and personal-import pathways, against a destination-country prescription and the regulatory paperwork specific to each jurisdiction.
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How Reserve Meds coordinates Wayrilz
- Patient or treating physician submits a named-patient request.
- Clinical team verifies appropriateness of Wayrilz for the patient and destination country.
- Treating physician issues prescription and clinical justification.
- Country-specific NPP / personal-import documentation is prepared.
- Wayrilz is sourced from a DSCSA-compliant US specialty wholesaler with full serial traceability.
- Shipment is coordinated to the patient's physician or hospital pharmacy (cold-chain where required).
Access by country
Reserve Meds publishes a detailed country deep-dive for Wayrilz in every market we coordinate. Each page below covers the destination-country regulatory pathway (named-patient framework), real costs in local currency and USD, indicative timelines, physician-credential requirements, and cold-chain handling for the route into that country. Tap any country to read the full deep-dive.
Start a request for Wayrilz
Submit a 60-second intake. Our clinical team will reach out as our first cohort opens with case-specific feasibility, timeline, and a formal quote.
Frequently asked questions
How can I get Wayrilz if it is not approved or available in my country?
Reserve Meds coordinates US-sourced Wayrilz for patients through a physician-led, named-patient cross-border pathway. Your treating physician provides the prescription and clinical justification; Reserve Meds prepares the named-patient documentation for your country and arranges DSCSA-compliant US sourcing and delivery to your physician or hospital pharmacy.
Can I access Wayrilz through named-patient or compassionate-use import?
Yes. Named-patient access (also called compassionate use or personal import) is the core route Reserve Meds operates for Wayrilz. Eligibility and paperwork depend on the regulator in your country, and Reserve Meds maps the specific pathway for each market it coordinates.
Do I need a prescription to access Wayrilz through Reserve Meds?
Yes. Reserve Meds is not a pharmacy and does not prescribe. A valid prescription and clinical justification from your treating physician are required, and all clinical decisions remain with your physician.
How does Reserve Meds deliver Wayrilz to a patient?
Reserve Meds sources Wayrilz from a DSCSA-compliant US specialty supplier with full traceability and coordinates delivery to your treating physician or hospital pharmacy, with appropriate handling for the product.
How long does it take, and what does Wayrilz cost through Reserve Meds?
After a short intake, the clinical team responds within one business day with case-specific feasibility, an indicative timeline, and a formal written quote. Cost depends on the destination, the prescribed regimen, and the duration of therapy, and is confirmed in writing before anything proceeds.
How do I start a request for Wayrilz?
Submit a 60-second intake through the Reserve Meds patient portal, or message the concierge team on WhatsApp. A named coordinator follows up within 24 hours.