Brinsupri (brensocatib)
Non-cystic fibrosis bronchiectasis in adults · Pulmonology (NCFBE)
About Brinsupri
Brinsupri (brensocatib) is an oral, once-daily dipeptidyl peptidase 1 (DPP1) inhibitor developed by Insmed. It is approved by the US FDA to reduce the frequency of pulmonary exacerbations in adults with non-cystic fibrosis bronchiectasis (NCFBE), a chronic inflammatory airway disease with no previously approved targeted therapy.
Brensocatib works by blocking activation of neutrophil serine proteases in the bone marrow, lowering the neutrophilic airway inflammation that drives exacerbations in NCFBE. The Phase 3 ASPEN trial showed a significant reduction in annualised exacerbation rate versus placebo.
Reserve Meds coordinates Brinsupri access for international patients through Named Patient Program and personal-import pathways where the drug is not yet locally registered. Eligibility requires a confirmed NCFBE diagnosis and a prescription from a pulmonologist in the destination country.
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How Reserve Meds coordinates Brinsupri
- Patient or treating physician submits a named-patient request.
- Clinical team verifies appropriateness of Brinsupri for the patient and destination country.
- Treating physician issues prescription and clinical justification.
- Country-specific NPP / personal-import documentation is prepared.
- Brinsupri is sourced from a DSCSA-compliant US specialty wholesaler with full serial traceability.
- Shipment is coordinated to the patient's physician or hospital pharmacy (cold-chain where required).
Access by country
Reserve Meds publishes a detailed country deep-dive for Brinsupri in every market we coordinate. Each page below covers the destination-country regulatory pathway (named-patient framework), real costs in local currency and USD, indicative timelines, physician-credential requirements, and cold-chain handling for the route into that country. Tap any country to read the full deep-dive.
Start a request for Brinsupri
Submit a 60-second intake. Our clinical team will reach out as our first cohort opens with case-specific feasibility, timeline, and a formal quote.
Frequently asked questions
How can I get Brinsupri if it is not approved or available in my country?
Reserve Meds coordinates US-sourced Brinsupri for patients through a physician-led, named-patient cross-border pathway. Your treating physician provides the prescription and clinical justification; Reserve Meds prepares the named-patient documentation for your country and arranges DSCSA-compliant US sourcing and delivery to your physician or hospital pharmacy.
Can I access Brinsupri through named-patient or compassionate-use import?
Yes. Named-patient access (also called compassionate use or personal import) is the core route Reserve Meds operates for Brinsupri. Eligibility and paperwork depend on the regulator in your country, and Reserve Meds maps the specific pathway for each market it coordinates.
Do I need a prescription to access Brinsupri through Reserve Meds?
Yes. Reserve Meds is not a pharmacy and does not prescribe. A valid prescription and clinical justification from your treating physician are required, and all clinical decisions remain with your physician.
How does Reserve Meds deliver Brinsupri to a patient?
Reserve Meds sources Brinsupri from a DSCSA-compliant US specialty supplier with full traceability and coordinates delivery to your treating physician or hospital pharmacy, with appropriate handling for the product.
How long does it take, and what does Brinsupri cost through Reserve Meds?
After a short intake, the clinical team responds within one business day with case-specific feasibility, an indicative timeline, and a formal written quote. Cost depends on the destination, the prescribed regimen, and the duration of therapy, and is confirmed in writing before anything proceeds.
How do I start a request for Brinsupri?
Submit a 60-second intake through the Reserve Meds patient portal, or message the concierge team on WhatsApp. A named coordinator follows up within 24 hours.