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Grafapex, antibody candidate

Preparative conditioning regimen for allogeneic hematopoietic stem cell transplantation in adult and pediatric AML or… · Hematology/oncology (transplant conditioning)

About Grafapex

Grafapex (treosulfan) is manufactured by medac GmbH (US commercial rights: preparative conditioning regimen for allogeneic hematopoietic stem cell transplantation in adult and pediatric AML or MDS patients 1 year and older. It is an Alkylating-agent injection (in combination with fludarabine) approved by the US FDA in 2025 and may be accessible to international patients through Named Patient Program or personal-import pathways.

How Reserve Meds coordinates Grafapex

  1. Patient or treating physician submits a named-patient request.
  2. Clinical team verifies appropriateness of Grafapex for the patient and destination country.
  3. Treating physician issues prescription and clinical justification.
  4. Country-specific NPP / personal-import documentation is prepared.
  5. Grafapex is sourced from a DSCSA-compliant US specialty wholesaler with full serial traceability.
  6. Shipment is coordinated to the patient's physician or hospital pharmacy (cold-chain where required).

Access by country

Reserve Meds publishes a detailed country deep-dive for Grafapex in every market we coordinate. Each page below covers the destination-country regulatory pathway (named-patient framework), real costs in local currency and USD, indicative timelines, physician-credential requirements, and cold-chain handling for the route into that country. Tap any country to read the full deep-dive.

Start a request for Grafapex

Submit a 60-second intake. Our clinical team will reach out as our first cohort opens with case-specific feasibility, timeline, and a formal quote.

Join the Grafapex waitlist