Poherdy (pertuzumab-dpzb, biosimilar to Perjeta)
Named-patient access overview. Poherdy is coordinated by Reserve Meds for international patients via physician-led cross-border sourcing.
About Poherdy
Poherdy (pertuzumab-dpzb) is a biosimilar to pertuzumab, the reference humanized IgG1 monoclonal antibody marketed by Genentech and Roche as Perjeta. Pertuzumab binds the HER2 receptor at its dimerization domain (subdomain II) and blocks HER2 from pairing with HER3, HER4, and EGFR. This complements trastuzumab, which binds a different HER2 epitope, and the combination produces a more complete blockade of HER2 signaling in HER2-positive breast cancer.
Poherdy is administered by intravenous infusion and is typically given in combination with trastuzumab plus a taxane chemotherapy backbone. Reference-product indications for pertuzumab include neoadjuvant, adjuvant, and metastatic HER2-positive breast cancer settings. Biosimilar-specific indication coverage and any carve-outs should be confirmed against the current FDA label for pertuzumab-dpzb before prescribing.
For international patients, Poherdy is sourced by Reserve Meds from a DSCSA-compliant US specialty wholesaler with full serial traceability and may be accessible via Named Patient Program or personal-import pathways depending on destination country.
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How Reserve Meds coordinates Poherdy
- Patient or treating physician submits a named-patient request.
- Clinical team verifies appropriateness of Poherdy for the patient and destination country.
- Treating physician issues prescription and clinical justification.
- Country-specific NPP / personal-import documentation is prepared.
- Poherdy is sourced from a DSCSA-compliant US specialty wholesaler with full serial traceability.
- Shipment is coordinated to the patient's physician or hospital pharmacy (cold-chain where required).
Access by country
Reserve Meds publishes a detailed country deep-dive for Poherdy in every market we coordinate. Each page below covers the destination-country regulatory pathway (named-patient framework), real costs in local currency and USD, indicative timelines, physician-credential requirements, and cold-chain handling for the route into that country. Tap any country to read the full deep-dive.
Start a request for Poherdy
Submit a 60-second intake. Our clinical team will reach out as our first cohort opens with case-specific feasibility, timeline, and a formal quote.
Frequently asked questions
How can I get Poherdy if it is not approved or available in my country?
Reserve Meds coordinates US-sourced Poherdy for patients through a physician-led, named-patient cross-border pathway. Your treating physician provides the prescription and clinical justification; Reserve Meds prepares the named-patient documentation for your country and arranges DSCSA-compliant US sourcing and delivery to your physician or hospital pharmacy.
Can I access Poherdy through named-patient or compassionate-use import?
Yes. Named-patient access (also called compassionate use or personal import) is the core route Reserve Meds operates for Poherdy. Eligibility and paperwork depend on the regulator in your country, and Reserve Meds maps the specific pathway for each market it coordinates.
Do I need a prescription to access Poherdy through Reserve Meds?
Yes. Reserve Meds is not a pharmacy and does not prescribe. A valid prescription and clinical justification from your treating physician are required, and all clinical decisions remain with your physician.
How does Reserve Meds deliver Poherdy to a patient?
Reserve Meds sources Poherdy from a DSCSA-compliant US specialty supplier with full traceability and coordinates delivery to your treating physician or hospital pharmacy, with appropriate handling for the product.
How long does it take, and what does Poherdy cost through Reserve Meds?
After a short intake, the clinical team responds within one business day with case-specific feasibility, an indicative timeline, and a formal written quote. Cost depends on the destination, the prescribed regimen, and the duration of therapy, and is confirmed in writing before anything proceeds.
How do I start a request for Poherdy?
Submit a 60-second intake through the Reserve Meds patient portal, or message the concierge team on WhatsApp. A named coordinator follows up within 24 hours.